Reliability and validity of the Vietnamese version of the FOSQ-10 questionnaire in patients with obstructive sleep apnea

08/10/2021 537 lượt xem

Nguyen Cao Minh Uyen, Vu Tran Thien Quan (Thesis, University of Medicine and Pharmacy, Ho Chi Minh City; 2019)

ABSTRACT

Background: Obstructive Sleep Apnea (OSA) significantly impacts the functional outcomes and daily quality of life (QoL) of affected individuals. This study aims to evaluate the clinical and polysomnographic features of individuals with obstructive sleep apnea (OSA) and to validate the psychometric aspects of the Vietnamese version of the Functional Outcomes of Sleep Questionnaire (FOSQ-10).

Methods: A cross-sectional study was performed on 112 patients, including 84 OSA and 28 snoring, at the University Medical Center. The FOSQ-10 and the Pittsburgh Sleep Quality Index (PSQI) were used as research tools. Validation methods included assessing content validity (I-CVI), face validity, internal consistency (Cronbach’s alpha), and construct validity through Exploratory Factor Analysis (EFA).

Results: The OSA group was mostly male (71%) and had an average age of 52.62 ± 14.47 years. Polysomnography showed that 58.3% of patients had severe OSA, with a median AHI of 36.3 (IQR: 18.35–56.48) events/hour and a median nadir SpO2 of 75% (IQR: 68-80%).

The Vietnamese FOSQ-10 demonstrated excellent content validity (I-CVI = kappa = 1.00) and strong face validity, as patients found the questionnaire easy to understand and relevant to their condition. The internal consistency was high (Cronbach’s alpha = 0.782), and test – retest reliability reached an excellent level (0.969). EFA found a structure with three factors: Productivity, Social Interference, and Activity Level/Social Outcome. All ten items had factor loadings greater than 0.55.

Concurrent validity was confirmed by a statistically significant correlation with the PSQI (rs = -0.352). Additionally, the FOSQ-10 successfully discriminated between patients with poor sleep quality (PSQI ≥ 5) and those with good sleep quality. The median total FOSQ-10 score was 15.31 (IQR: 12.67–17.70), and the “Intimacy and Sexual Relationships” domain had the lowest score, with a median of 2.0.

Conclusion: The Vietnamese validation of the FOSQ-10 is a reliable and valid instrument for assessing the impact of OSA on functional outcomes. The study highlights that a majority of OSA patients present with severe disease and significant impairment across multiple quality-of-life domains.

Keywords: Obstructive Sleep Apnea, FOSQ-10, Quality of Life, Validation, Vietnam.